Can Resveratrol Help Diabetes

There are several supplements and medication that are of great assistance when it comes to diabetes’ glucose control. Nevertheless, you need to know what to do, get reliable information that are scientific clinical proven for you to get the right resveratrol to help diabetes. This is important since people have been asking this question: can resveratrol help diabetes? This assists in terms of having important information in terms of how resveratrol helps diabetes.

Apart from not being formal medication, resveratrol is neither a regulated nor a prescribed medication. According to medical experts, this is among the dietary supplement, which originated from the red grapes’ skin. Apart from the red grape extract or skin, resveratrol supplements have extracts obtained from the Polygonum cuspidatum; this is a Chinese and Japanese knotweed plant.

Some red wine variability is known for containing more resveratrol, unlike others. For instance, pinot noir together with merlot have more for each 5-ounce glass, unlike cabernet sauvignon. Excitingly, resveratrol is found in certain berries and peanut. As compared to resveratrol in most over-the-counter supplements, in wine and foods, the resveratrol’s amount is always less.

resveratrol, grape

Studies and Claims

These claims about resveratrol are ever infinite; thus is from having healthier and longer lifespan to weight and anything in between. The claims are related to cancers, neurodegenerative diseases and cardiovascular treatment and prevention. The main health claim is in accordance with the resveratrol supplementation’s diabetes, which encompasses prevention of insulin resistance and enhanced glycemic control. Note this; prevention of insulin resistance is of great importance when it comes to inhibiting diabetes from becoming a worse health condition or developing. It is not meant for treating diabetes.

In resveratrol, antioxidant molecules are categorized under polyphenols class, which is referred to stilbenes. Resveratrol stated to increase, becoming popular, back in 1990s. During that period, red wine, this has been lowering cancers and cardiovascular diseases’ prevalence, especially for those that are related to “French Paradox.” A conundrum, which is the French Paradox, can be used to describe low incidences of cancers, cardiovascular diseases and diabetes among individuals who have been consuming French diet that have saturated fat and in the red wine, they are moderate.

Supporting Facts

The positive thing about the research is that in diabetes, resveratrol effect is happening. Nevertheless, according to PubMed search, more than 8600 published studies on the resveratrol and 580 related to diabetes, and only just 250 of them were human-related subjects. Therefore, the following are some research highlights in terms of answering the question ‘can resveratrol help diabetes?

According to the Australian study, which was published in the American Journal of Clinical Nutrition confirmed no improvement as far as body weight, glycemic control, gastric or calorie intake emptying is concerned in the type-II diabetes among the patients who take resveratrol. What is more, the subjects were not related to the diabetes medication, though they were given 500 mg resveratrol for five weeks, twice a day. The subjects’ mean baseline of HbA1c was found to be 6.4%.

The meta-analysis meant for investigating how certain various lab parameters within the diabetes subjects are affected by resveratrol easily revealed the improvement in the HbA1c, blood pressure and creatinine. Nevertheless, in insulin resistance, in a fasting glucose, or blood lipids, for instance, cholesterol, LDL, HDL and triglycerides.

According to an Indian research, an improvement was reflected in the HbA1c, total blood pressure and cholesterol in the type-II diabetes subject, in which 250 mg resveratrol was taken for about three months, twice a day. On HDL, body weight or LDL, no effect was realized. Remarkably, the subjects started with much high HbA1c value, the mean was 9.99% and thus was unlike the Australian research that has been mentioned above. In addition, patients were taken for a long duration.

According to a study that was carried out in Spain that trialed, for one year, the supplement that was extracted from the grape in patient with type-II diabetes patients. According to the glucose, HbA1c, or lipids’ clinical markers or the body weight, much interest was given to antiinflammatory effects, which were very clear. Pro-inflammatory cytokine, which are responsible for increasing inflammation, with the resveratrol supplementation are always down-regulated.

Side Effects

While looking for what is resveratrol and what does it do, researchers have not managed to find severe side effects of resveratrol. Some mild gastrointestinal issues, which incorporate abdominal pain, nausea, diarrhea and flatulence, have been reported in the human subjects, which require at least 1 gram per day for 29 days, of resveratrol.

Suggested Drugs

Since metabolic pathway related resveratrol has been following through liver, interaction with some forms of the prescription meditation can be experienced. Nevertheless, there is no much evidence to prove this since scholars have not studied this in detail. Also, interactions existing between antiplatelet and anticoagulant medications and or resveratrol are not always based on the clinical evidence, but experimental evidence. Scholars have not managed to document interactions between nutrients, foods, or herbs and resveratrol.

Drug-resveratrol related interactions incorporate treatments in these drug categories; nevertheless, not essentially all treatment in every category:

  • Anti-arrhythmic agents
  • Calcium channel antagonists
  • Immunosuppressant
  • Benzodiazepines
  • Antihistamines
  • Drugs meant for treating erectile dysfunction
  • HMG-CoA reductase inhibitors


The botanical supplements are under “dietary supplements” category, which is in the 1994 Federal Dietary Supplement Health and Education Act’s vocabulary. Dietary supplements cannot be standardized in America. So, it is impossible for a consumer to be 100% positive based on what is being purchased in supplement capsules or bottles. The Food and Drug Administration developed Good Manufacturing Practices, in 2007, with the aim of standardizing and improving the available supplements’ quality on different markets. From the supplement label, it can be somehow difficult to find out if the methods being used by manufacturers are of great quality or not. What is more, testing supplement for efficacy is not allowed by federal law. Nevertheless, this is something that buyers ought to know in relation to answering the question: can resveratrol help diabetes?